Current Issue
Cognitive impairment of neuromyelitis optica spectrum disorders and its research progress
Date：
2022-01-21
HE Shao-yue, WANG Xiao-ming. (Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Institute of Neurology, North Sichuan Medical College, Nanchong, Sichuan 637000, China.)
[ Abstract ] Neuromyelitis optica spectrum disorders is a group of immune-mediated inflammatory demyelinating diseases of the central nervous system, mainly involving the optic nerve and spinal cord. It can also be manifested as acute brainstem syndrome, acute diencephalon syndrome, cerebral syndrome and medulla postrema syndrome. More and more studies have shown that NMOSD patients have cognitive impairment, but the onset of NMOSD is hidden, and it is easy to be ignored clinically. This paper reviews the research progress of cognitive impairment of NMOSD from the aspects of neuropsychology, neuropathology, immunology and neuroimaging.
[ Key words ] Neuromyelitis optica spectrum disorders; Cognitive impairment; Multiple sclerosis